Biennial Workshop

Biennial Workshop

Spanning the spectrum of social behavior:
towards more translationally relevant animal models

Spanning the spectrum of social behavior:
towards more translationally relevant animal models

Rome, Italy · 24-26 June 2022

Rome, Italy · 24-26 June 2022

Programme

  • 14:00-17:00

    Arrival and check-in

    17:00-17:15

    Welcome from Co-Chairs

    Marco Venniro, Sam Golden, Daniele Caprioli, Valeria Carola, Valentina Ferretti, Carlo Cifani

    17:15-18:15

    EBPS Power Hour:

    Leslie Ramsey (National Institute on Drug Abuse, USA) & Kimberlei Richardson (Howard University College of Medicine, USA)

    The 2022 EBPS Workshop Power Hour is an optional informal dynamic and interactive gathering open to all meeting participants. It is designed to help address the challenges women and under-represented minorities face in science and support the professional growth of women and under-represented minorities in our communities by providing an open forum for discussion and mentoring.

    18:15-19:00

    Mentor-Mentee Meeting

    19:00-21:00

    Welcome Reception (snacks and beverages provided)

  • 8:30-9:30

    Keynote Lecture 1

    Camilla Bellone (Universite de Geneve, Switzerland)

    Neuronal circuits underlying social motivation

    9:30-11:00

    SESSION 1: The importance of social behavior in addiction neuroscience

    Discussion Leaders: Yavin Shaham (National Institute on Drug Abuse, USA), Marco Venniro (University of Maryland School of Medicine, USA)

    Bernard Johnson (Wake Forest University, USA)

    Influence of social status on cocaine self-administration, dopamine and kappa receptor availability in female and male Cynomolgus monkeys

    Christelle Baunez (Institute of Neurosciences Timone, Marseille, France)

    Modeling the social context during drug intake in the rat: role of the subthalamic nucleus as neurobiological substrate

    Michael Bardo (University of Kentucky)

    Peer-elicited drug seeking

    Irene Perini (Linkoping University, Sweden)

    Probing human social behavior in experimental settings

    11:00-11:30

    Coffee break and snacks

    11:30-13:00

    SESSION 2: Affiliate social reward and social play in rats

    Discussion Leader: Viviana Trezza (Roma 3 University, Italy)

    Marijke Achterberg (Utrecht University, The Netherlands)

    Pathways to play: Effects of DA-neuron activation on the expression of and motivation for social play

    Inbal Ben-Ami Bartal (Tel Aviv University, Israel)

    Neural correlates of prosocial behavior in rats

    Alexa H. Veenema (Michigan State University, USA)

    Neural circuitry of social play: involvement of oxytocin and vasopressin

    Gerald Zernig (Innsbruck University, Austria)

    Conditioned place preference for dyadic social interaction in rats and mice: findings and caveats

    13:00-14:30

    Lunch

    14:30-16:00

    SESSION 3: Affiliative social reward in mice and voles

    Discussion Leader: Camilla Bellone (Universite de Geneve, Switzerland)

    Francesco Papaleo (Istituto Italiano di Tecnologia, Italy)

    Cortico-cortical transfer of socially derived information gates emotion discrimination

    Leslie Ramsey (National Institute on Drug Abuse, USA)

    In search of prefrontal cortical neuronal ensembles that encode volitional social interaction in mice

    Ann Clemens (University of Edinburgh, UK)

    Neural circuits of kinship behaviour

    Zoe Donaldson (University of Colorado Boulder, USA)

    Prolonged partner separation erodes transcriptional signatures of pair bonding in prairie voles

    16:00-16:30

    Coffee break and snacks

    16:30-17:30

    Keynote Lecture 2

    Nora Volkow (National Institute on Drug Abuse, USA)

    Social determinants of drug use and addiction

    17:30-19:00

    Poster Session 1 (odd numbers)

    19:30-24:00

    Gala Dinner at “Palazzo Brancaccio”

  • 8:30-9:30

    Keynote Lecture 3

    Alon Chen (Weizmann Institute, Israel)

    A paradigm shift in mouse phenotyping to bridge the translational gap in psychiatry

    9:30-11:00

    SESSION 4: Aggression as a social reinforcer in rodents

    Discussion Leaders: Klaus Miczek (Tuft University, USA), Sam Golden (Washington University, USA)

    Emily Newman (Harvard University, USA)

    An amygdala Crh+ cell activity signature for attack initiation

    Valeria Carola (Sapienza University of Rome, Italy)

    Exposure to a threatening social environment at an early age induces permanent behavioral and neurodevelopmental alterations

    Christian Broberger (Stockholm University, Sweden)

    A phenotype-dimorphic center for aggressive behaviour in the mouse hypothalamus

    Aki Takahashi (Tsukuba University, Japan)

    Neural circuit for aggressive arousal induced by provocation in male mouse

    11:00-11:15

    Coffee break and snacks

    11:15-12:15

    SESSION 5: Data Blitz for student 1

    Discussion Leaders: Ingrid Reverte (Sapienza University of Rome, Italy), Clarissa Catale (IBENS, École Normale Supérieure, France)

    Maria Bove (University of Foggia, Italy)

    N-acetylcysteine reduces repetitive behaviours and neuroinflammation in a mouse model of ketamine-induced Autism Spectrum Disorders-like symptoms

    Maria Giulia Coccia (University of Milan, Italy)

    Prosocial and selfish choices depend on cortico-amygdala reciprocal connections

    Cody Lis (University of Maryland School of Medicine, USA)

    A role for the OFC in the flexibility of social vs drug choice

    Ginevra D’Ottavio (Sapienza University of Rome)

    Evidence for heroin-induced social isolation in the rat

    Francesca Mottarlini (University of Milan, Italy)

    Activity-based anorexia alters cortical and hippocampal structural plasticity during adolescence: effects on cognition

    Joel Raymond (University of Sydney, Australia)

    Exploring parameters influencing social motivation in rats using behavioural economics and social operant conditioning

    12:15-12:45

    Lunch

    12:45-13:15

    Poster Session 2 (even numbers)

    13:15-14:15

    SESSION 6: Data Blitz for student 2

    Discussion Leaders: Ingrid Reverte (Sapienza University of Rome, Italy), Clarissa Catale (IBENS, École Normale Supérieure, France)

    Yair Shemesh (Weizmann Institute, Israel)

    Territorial aggression is mediated via two parallel neuropeptide pathways

    Antonino Casile (University of Camerino, Italy)

    A new animal model of Internet Gaming Disorder (IGD): sexual differences in behavior and brain activity

    Kimberly Papastrat (University of Maryland School of Medicine, USA)

    Olfaction drives socio-sensory buffering of drug choice

    Henriette Nyberg (Oslo University, Norway)

    Prenatal opioid exposure and social play behavior

    Bree Humburg (University of Kentucky, USA)

    A social peer renews cocaine seeking: a potential role of oxytocin

    Jackson Ham (University of Lethbridge, Canada)

    I choose you: rats show partner preferences in social play

    14:15-15:15

    Keynote Lecture 4

    Lique Coolen (Kent State University, USA)

    Sexual reward experiences influence drug seeking behavior

    15:15-16:45

    SESSION 7: Technologies to advance the study of complex social behavior

    Discussion Leader: Ofer Yizhar (Weizmann Institute, Israel)

    Ann Kennedy (Northwestern University, USA)

    Hypothalamic correlates of internal motivational states in interacting mice

    Cornelius Gross (European Molecular Biology Laboratory, Italy)

    Experience-dependent remodeling of an innate social fear circuit

    Mightex Systems - Catherine Thomas & Francisco Rodrigues

    Multi-region cellular resolution imaging and optogenetics during social behaviours with the Mightex OASIS Implant

    Inscopix - Fabrizio Sitzia

    Miniscope imaging during free behavior with the Inscopix Platform

    16:45-17:00

    Coffee Break

    17:00-18:00

    Keynote Lecture 5

    Ofer Yizhar (Weizmann Institute, Israel)

    Representation of social information and autism-associated dysfunction in the mouse prefrontal cortex

    18:00-19:00

    Departure

  • When preparing your poster, please remember that its maximum size is 80 x 120 cm (width x height). Note that the orientation is portrait, not landscape.

    Posters with an odd number will be presented during Poster Session 1 (Saturday, 25 June, 17:30-19:00). Posters with an even number will be presented during Poster Session 2 (Sunday, 26 June, 12:45-13:15).

    P.1 Alice Abbondanza, Prague, Czech Republic
    Deletion of beta2* nicotinic acetylcholine receptors in striatal interneurons inhibit striatal activity and control striatal-dependent behaviors

    P.2 Inês Amaral, Innsbruck, Austria
    Molecular candidates in the nucleus accumbens shell involved in the protective effect of social interaction when available as an alternative to cocaine

    P.3 Augusto Anesio, São Paulo, Brazil
    Selective inhibition of nucleus acumbens neuronal ensembles potentiates cocaine seeking after forced abstinence

    P.4 Coral Aronovici, Tel Aviv, Israel
    Neuronal ensembles of alcohol memories express a unique transcriptional fingerprint

    P.5 Lucy Babicola, Rome, Italy
    Intergenerational transmission of mother-pups bond interference and psychopathological consequences: the role of paternal experience

    P.6 Francis Bambico, St. John's, Canada
    Cannabidiolic acid methyl ester (HU-580) reverses MK-801-induced social and behavioural deficits

    P.7 Margherita Barbetti, Parma, Italy
    Peripheral inhibition of FAAH activity prevents social stress-induced increase in pro-inflammatory cytokines and social avoidance behavior in male rats

    P.8 Emilie Bartsoen, Leuven, Belgium
    Exploratory analysis of rat ultrasonic vocalizations emitted during the acoustic startle response test

    P.9 Federica Benvenuti, Camerino, Italy
    Effect of early social isolation on alcohol-related behaviors in alcohol-preferring msP and non-preferring Wistar rats

    P.10 Paula Bianchi, São Paulo, Brazil
    Inactivation of basolateral amygdala neuronal ensembles impairs the context-induced reinstatement of ethanol seeking

    P.11 Joeri Bordes, Munich, Germany
    Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress

    P.12 Catarina Borges, Montreal, Canada
    The effect of chemogenetic inhibition of the pPVT on food deprivation-induced relapse to heroin seeking after punishment-imposed abstinence, in male and female rats

    P.13 Anna Maria Borruto, Mannheim, Germany
    Thalamic inputs to the central amygdala mediate pain-related anxiety in female mice

    P.14 Valeria Buzzelli, Rome, Italy
    Effects of cannabidiol on autistic-like traits in a genetic model of autism based on FMR1 deletion in rats

    P.15 Clarissa Catale, Paris, France
    Early life social stress causes sex- and region-dependent dopaminergic changes that are prevented by minocycline

    P.16 Ilenia Ceccarelli, Rome, Italy
    From Skinner box to daily life: clinical translational validity of sign-tracker phenotype

    P.17 Magdalena Chrószcz, Kraków, Poland
    Rewarding effects of interactions with siblings across adolescence in mice

    P.18 Lorenzo Ciano, Genoa, Italy
    Synaptic alterations in the auditory cortex and hippocampus underlie social deficits in the synapsin II knockout mouse

    P.19 María Teresa Colomina, Tarragona, Spain
    Prenatal chlorpyrifos exposure alters social behavior in mice depending on APOE genotype and sex

    P.20 Laisa De Siqueira Umpierrez, Sydney, Australia
    Cannabis extract alone and in combination with cannabidiol reduces relapse to methamphetamine and locomotor sensitization

    P.21 Livia Di Crescenzo, Leuven, Belgium
    Lack of the autism candidate gene Reelin in somatostatin inhibitory cortical neurons leads to altered developmental trajectories in mouse pups: a pilot study

    P.22 Tamara Diamanti, Rome, Italy
    Characterization of sociability traits during development in the R451C Neuroligin3 monogenic mouse of autism

    P.23 Carolyn Doty, Baltimore, USA
    Cerebellum activity mediates social craving

    P.24 Rita El Azali, Guelph, Canada
    The effects of punishment contingency on oral morphine consumption in male and female rats

    P.25 Noa Eren, Rehovot, Israel
    Complex behavioral phenotyping in groups of ASD-like mice reveals modulation of behavior by the social environment

    P.26 Nicholas Everett, Camperdown, Australia
    A novel pharmacotherapy for increasing preference for social reward over intravenous methamphetamine in female rats

    P.27 Cristiane Favoretto, São Paulo, Brazil
    Impacts of maternal separation stress on ethanol intake, CB1 expression and neuronal activation levels in adolescent mice 

    P.28 Rebecca Figge, Cologne, Germany
    Antagonistic control of social interaction by leptin receptor-expressing and neurotensin-expressing neurons in the lateral hypothalamus

    P.29 Valeria Gigli, Rome, Italy
    COVID-19 consequences on motivational functioning: an ecological and laboratory study

    P.30 Macarena González Portilla, Valencia, Spain
    Attenuating effects of oleoylethanolamide on cocaine-induced place preference in socially defeated mice: comparing acute and subchronic treatment

    P.31 Guilherme Horta, Mainz, Germany
    The K63 deubiquitinase CYLD modulates autism-like behaviors in mice

    P.32 Azka Khan, Rome, Italy
    Role of microglia in reconsolidation-resistant fear memories 

    P.33 Elmira Khatamsaz, Biberach an der Riß, Germany
    Role of default mode network in social dysfunction

    P.34 Tod Kippin, Santa Barbara, USA
    Associations between mother-offspring social behavior and cocaine responsiveness in adulthood

    P.35 Sara Kroll, Zurich, Switzerland
    Associations between the endocannabinoid system and drug craving in chronic cocaine users

    P.36 Filippo La Greca, Milan, Italy
    Dissecting the neural bases behind observational learning of complex social behaviors

    P.37 Luisa Lo Iacono, Rome, Italy
    MicroRNA-34 is involved in chronic social defeat-induced vulnerability to mood disorders and cardiac mitochondrial dysfunctions

    P.38 Samantha Malone, Lexington, USA
    Peer-induced remifentanil seeking in male and female rats

    P.39 Camilla Mancini, Camerino, Italy
    Investigating the effects of a stable attachment figure in an unstable maternal environment: the role of oxytocin

    P.40 Claudia Marchetti, Rome, Italy
    Effect of social choice-induced voluntary abstinence on incubation of methamphetamine craving and related expression of AMPA receptor in nucleus accumbens core

    P.41 Allison McDonald, Amsterdam, The Netherlands
    Alcohol use despite negative consequences: Identifying associated brain circuits & behavioural patterns

    P.42 Martina Montanari, Rome, Italy
    A potential pathophysiological role of neuroinflammation in the ventral striatum of the R451C-Nlgn3 mouse model of autism

    P.43 Leonardo Nardi, Mainz, Germany
    Neuroanatomical mapping of functional activation during social interaction in a model for idiopathicautism spectrum disorder (ASD) at adulthood

    P.44 Virginia Papagni, Rome, Italy
    MicroRNA-34 as possible mediator for acquisition of Avoidance after Chronic Social Defeat

    P.45 Alice Passeri, Rome, Italy
    The long-lasting effects of attachment bond alteration: the role of oxytocin

    P.46 Nicholas Pintori, Verona, Italy
    Synergistic effect of social living, Environmental Enrichment and fluoxetine association in inhibiting sucrose-seeking renewal in mice

    P.47 Alessandro Piva, Verona, Italy
    Brief environmental enrichment stimulation increases contextual-induced sucrose-seeking at renewal and memory reconsolidation in rats

    P.48 Alessandro Rava, Rome, Italy
    Characterization of the endocannabinoid system in a genetic model of autism based on FMR1 deletion in rats

    P.49 Marina Reguilón Romero, Valencia, Spain
    Voluntary pre-exposure to exercise during adolescence prevents the increase in ethanol consumption induced by social defeat in stress-susceptible adult mice

    P.50 Diego Ruiz Sobremazas, Almería, Spain
    Effects of prenatal Particulate Matter <10nm exposure on rats: analysis of pre- and post-weaning social behavior

    P.51 Alexia Santos, São Paulo, Brazil
    Context-induced reinstatement of ethanol in C57BL/6 mice

    P.52 Martino Schettino, Rome, Italy
    The acute effects of intrusive thinking on neurotransmission within anterior cingulate cortex in pathological and non-pathological worriers: A 1H magnetic resonance spectroscopy an ecological momentary assessment study

    P.53 Jakob Shaykin, Lexington, USA
    Social isolation combined with adolescent voluntary ethanol exposure increases subsequent addiction vulnerability

    P.54 Olesya Shevchouk, Göteborg, Sweden
    Mapping the domains of social behaviour regulated by GLP-1 signaling

    P.55 Anita Sikic, Guelph, Canada
    The non-discrimination between cigarette smoke extract and nicotine in rats

    P.56 Fernando Silva, São Paulo, Brazil
    The association between impulsive behavior and voluntary ethanol intake

    P.57 Franziska Stoller, Biberach an der Riß, Germany
    Manipulating a brain circuit associated with sociability by a two-recombinase-system

    P.58 Akseli Surakka, Mannheim, Germany
    Axonal oxytocin release in the paraventricular thalamus impairs social memory in female rats

    P.59 Karen Szumlinski, Santa Barbara, USA
    The ontogeny of alcohol-induced negative affect in C57BL/6J mice

    P.60 Valeria Tarmati, Rome, Italy
    Role of the anterior and posterior Paraventricular Nucleus of the Thalamus on Sign-Tracking in inbred C57BL/6J and DBA/2J mice

    P.61 Elena Tiddens, Brighton, United Kingdom
    The effect of volitional social interaction and naltrexone in an animal model for gambling disorder

    P.62 Cassandre Vielle, Marseille, France
    How the presence of a peer modulates drug intake: a key role of vocal communication mediated by the activity of the subthalamic nucleus in rats

    P.63 Lucie Vignal, Marseille, France
    Reversing escalated cocaine intake with social contact and optogenetic modulation of the subthalamic nucleus

    P.64 Markus Wöhr, Leuven, Belgium
    Multifaceted behavioral alterations and obesity in Myt1l haploinsufficient mice: implications for autism spectrum disorder

    P.65 Alicia Zumbusch, Montreal, Canada
    Chronic pain leaves motivation intact for two forms of sucrose reward

    P.66 Valeria Carola, Rome, Italy
    Telomere length is altered in early-life social stressed individuals during cocaine withdrawal